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While it takes a human action (the administration of a thiopurine drug) to trigger a manifestation of this relation in a particular person, the relation itself exists in principle apart from any human action.
The researchers used a drug to trigger increased tension in brown fat cells and found that the concept of activating tension can lead to burning calories, but much more work is needed to identify the right chemical compound that could do this effectively.
For these approaches to increase the therapeutic index of the active metabolite, the prodrug must be selectively activated in the tumor and the active metabolite must remain in the tumor for a reasonable time relative to the time it takes for the drug to trigger cell death.
Cells were incubated for 2 hr with the disaggregating drug at 20°C (3) or 16°C (4) prior to removing the drug to trigger re-aggregation over 1 hr.
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He is told to persuade another dealer to sell him just enough drugs to trigger a 15-year sentence, and perhaps to do the deal near a school, which adds another two years.Severe drug laws have unintended consequences.
The double dose of stimulants — from her tumor and the drug — seemed to trigger her psychotic break.
Then, we docked a series of drugs known to trigger ADRs via direct HLA interactions and we found that drugs like carbamazepine, fenofibrate, pazopanib, and simvastatin are predicted to have some binding interactions with the HLA-B*57 01 HLA-B*57 01
By stalling the formation of normal blood vessels and starving tumors of oxygen, the drugs appear to trigger cancer cells to build their own blood highways.
However, drugs known to trigger migraine, including CGRP and prostaglandin E2 (PGE2) [12] do not cause dural PPE, and there is no evidence of release of substance P in cephalic venous outflow during spontaneous migraine [56], in contrast to CGRP and PGE2.
Only conditions or drugs known to trigger apoptosis in Leishmania could induce asrRNA fragmentation and rRNA degradation.
Therefore, interest in pharmacological preconditioning has increased, and opioids were among the first drugs shown to trigger the cascades of preconditioning.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com