Sentence examples for drug to diffuse from inspiring English sources

A polymeric drug carrier primarily diffuses the drug molecules and chitosan as a mucoadhesive, cationic polymer assists the drug to diffuse easily during the initial incubation period (Zhou et al. 2001; Berscht et al. 1994).

The mathematical model allows the drug to diffuse through both cancer cells and the ECM.

Thus loading a microbubble with an active drug to diffuse through the barrier and target a specific area increases the usefulness and action of drug [ 119].

For drug experiments, we prepared drug-containing plates by spreading 300 μl of a 10× aqueous drug solution on a 35 mm diameter plate, then waiting at least 3 hr for the drug to diffuse into the agar.

This number of simulation steps was chosen arbitrarily in order to provide enough time for drug to diffuse to tumor center but also short enough to comply with the half life of known drugs.

Thus, it can be speculated that vascular normalization would increase the delivery of drug that have dissociated from the liposome across the tumor vasculature, allowing higher levels of drug to diffuse into a greater volume of tumor tissue.

This may create fluid pressure within the tumor that is much higher than in the tumor's blood vessels, making it hard for any cancer drugs to diffuse from the blood into the tumor.

EMT6 spheroids 275 350  μ m in diameter were incubated in 0.1 15 mM aminolevulinic acid (ALA) or 0.001 2 mM ALA-hexylester (h-ALA) to test the ability of both pro-drugs to diffuse into the spheroids and induce PpIX production.

In conclusion, we provided a comprehensive picture of the interaction of the two major fluoroquinolones ciprofloxacine and moxifloxacine with lipids, and elucidate fundamental issues such as the relationship between lipid chain conformation and orientation with changes in membrane properties as determined by Langmuir studies and the ability of drugs to diffuse through membranes.

In contrast to hydrophobic drugs, small hydrophilic drugs tend to diffuse from the PEG water phase to the body more quickly.

Thus, the drug has to diffuse through the thick viscous gel layer formed outside the polymeric matrix hence resulting in slower drug release or release over prolonged period of time [ 24].