Sentence examples for drug that binds from inspiring English sources

In the absence of doxycycline (dox), a drug that binds to tTA and prevents tTA from binding to the tetracycline responsive promoter (tetO), the resulting tTA can activate the expression of the tau-LacZ marker from the transgene: tetO-tau-lacZ:tTA*.

To determine whether the ERβ-dependent decrease in network formation observed in HEECs was also Sp1 dependent, cells were treated with Mithramycin A, an anti-cancer drug that binds to GC-rich regions of chromatin and prevents binding of Sp transcription factors.

During the 7-day experimental period, some rats were injected periodically with a specific EP4 agonist ONO-AE1-329 ONO-AE1-329 ONO-AE1-329 the EP4 receptor to mimic the actions of ligandrugnding; thatinjection site was on the tension side in the interproximal region bindsen toe firsthend sEP4nd molareceptor

Nobody could think of a good way of knocking out the oncogenes.' There were, however, a few specific successes, the greatest of which was cisplatin, a drug that binds to DNA and uses platinum compounds to interfere with cell division.

Differences in efficacy determine whether a drug that binds to a receptor is classified as an agonist or as an antagonist.

He further reasoned that one way this might be done is with a drug that binds to a cell's purine receptors, so that they cannot react when purines come along.

4– 6 The PIs are a class of antiretroviral drug that bind competitively to the viral protease enzyme that inhibits the cleavage of the gag-pol polyprotein.

Drugs that bind to imidazoline binding proteins have major physiological actions.

Consequently, the protein binding of drugs that bind primarily to albumin, such as midazolam and nifedipine, is expected to decrease, leading to increased clearance.

Among the three drugs that bound to the DNA-Topo I complex, SN-38 had the strongest relative binding affinity, and CPT had the weakest relative binding affinity.

Zolpidem had more impact on sleep than on amnesia, muscle relaxation, and the other effects associated with drugs that bind to gaba receptors.