Sentence examples for drug termination from inspiring English sources
Non-serious AEs were assessed and recorded from study drug initiation up to 8 h following study drug termination.
Patients have an appointment 1 month after randomisation (visit 2), at 3 months (visit 3) and then every 3 months until study drug termination (2 years).
In terms of safety, dronedarone was more favorable than amiodarone, which was associated with higher odds of study drug termination (OR = 6.65; 95% CI, 1.13 39.3).
After study drug termination, BP and HR were obtained at 2, 4, 6, 8, 12, 20, 30, and 60 min; then every 15 min for the next 3 h; then at 6 and 8 h.
Subjects could resume their oral BP medication(s) 4 h after study drug termination in the order previously prescribed, or had an appropriate antihypertensive regimen established under physician guidance.
In this regard, it should be noted that drug development termination at the clinical trials stage is not equivalent to efficacy failure.
Treatment-emergent adverse events (AEs) were defined as any untoward medical event that either occurred or worsened at any time after the first administration of the study drug through study termination or early termination.
Data on smoking, alcohol intake, previous illicit drug use and termination of pregnancy relied on self-reporting and it is possible that there may have been under-reporting.
Moreover, while combination treatment with rapamycin or PD0325901 led to the reduction of established tumors, upon termination of drug treatment the melanomas reappeared the presence of drug resistant melanoma-initiating cells in these mice.
However, termination of drug release from such a CRDDS at tdel and/or a declining drug input function towards the terminal phase of tdel from a first order kinetic CRDDS can have severe implications on plasma drug concentration and steady state fluctuations for a drug with very short half-life.
Because early termination of drug courses might indicate failure due to toxicity or inefficacy, the loss of information from these drug courses has the potential to bias the effectiveness estimates upwards.
