Sentence examples for drug secretion from inspiring English sources

Transporter-mediated drug secretion into canalicular networks was however only observed in sandwich-cultured hepatocytes.

The complexity of this transport machinery makes investigation of processes such as tubular drug secretion a continuous challenge for researchers.

At the level of the luminal membrane of renal proximal tubules, MDR-1 accelerates drug secretion into the urine.

In one case, assembly of TOMPs such as TolC, a channel involved in protein and drug secretion, appears to be dependent on BamA (Werner & Misra, 2005), while others such as PulD, one of the so-called secretins (Bayan et al., 2006), appear to be dependent on specific lipoproteins such as PulS for insertion into the OM (Collin et al., 2007).

Recent advances in engineered therapeutic delivery include temporal control of cytotoxin release, enzymatic activation of pro-drugs, and secretion of physiologically active biomolecules.

Interval institution or cessation of drugs effecting secretion may falsely imply changes in GFR.

This approach has already shown some success: drug-specific secretion of interferon-gamma was detected in lymphocytes isolated from HLA-B*57 01-positive HLA-B*57 01-positive HLA-B*57 01-positive short priming period [ 29].

As expected, increasing concentration of this drug decreased the secretion of luciferase temporary in a similar way to DTT treatment and correlated with an increase in BiP expression (Fig. 5E&F).

36 This drug induces prolactin secretion without any estrogenic or progestagenic effects.

The intestinal P-gp plays a main role in the fecal elimination of drugs by modulating reabsorption of the drug after hepatobiliary secretion.

As microfilament-disrupting agents, cytochalasins alter cell motility, adherence, secretion, drug efflux, deformability, morphology, and size, among many other cell properties critical to neoplastic cell pathology [ 1, 2].