Sentence examples for drug relations from inspiring English sources

Based on drugCIPHER-MS, a genome-wide map of biological fingerprints for 726 drugs is built, and unexpected drug relations, which imply potential novel drug applications and side effects, are generated.

By integrating TS and CS in pharmacological space and PPIs in genomic space, unexpected drug relations emerge, which demonstrate that the integration of existing multi-dimensional information may generate additional knowledge.

Systems pharmacology aims to integrate knowledge about drugs, drug-drug interactions, drug interactions with cells and organs, and drug relations to adverse events and desired effects in individual patients [ 1].

4) 85.3% of patients had any adverse event, 9.2% were serious without suspected drug relation; and in 32 patients a drug-relation was suspected.

Safety was evaluated by nature, severity, and drug relation of adverse events (AEs), graded according to National Cancer Institute Common Toxicity Criteria for Adverse Events (NCI-CTCAE v3.0) and reported by incidence.

At a significance level of 0.05 of the activity resemblance, 501 unexpected drug-drug relations are obtained (Table S1).

Based on drugCIPHER-MS, a genome-wide map of drug biological fingerprints for 726 drugs is constructed, within which unexpected drug-drug relations emerged in 501 cases, implying possible novel applications or side effects.

Applied to marketed drugs, a network of side-effect-driven drug-drug relations became apparent.

This system, developed as a pilot system using breast cancer as a test-bed, searches, documents, archives, and updates the gene-drug relations automatically.

Functional annotation of gene modules with gene-drug relations was performed using the ConsensusPathDB [ 20– 22] to provide biological pathway information for each gene set.

Secondly, the system provides a tool of querying candidate gene-drug relations, which by no means indicate a direct clinical application.