Sentence examples for drug memory from inspiring English sources

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However, effective and efficient strategies to reactivate drug memory remained elusive.

These demonstrations of drug memory reconsolidation impairment have been shown across addictive drugs, including cocaine and alcohol, as well as for heroin withdrawal memories (Hellemans et al., 2006; Milton & Everitt, 2010, 2012a; Milton, 2013).

Generally NMDA receptor antagonism is universally effective in preventing drug memory reconsolidation and there is an established link between NMDA receptor activation and ZIF268 expression in the amygdala at memory retrieval (Milton et al., 2008a).

In the case of CS cocaine memories, DCS can certainly potentiate reconsolidation and increase the impact of the CS on drug seeking measured subsequently, but we have not been able to demonstrate DCS enhancement of drug memory extinction (Lee et al., 2009).

Notwithstanding the conceptual and practical difficulties, the time is perhaps right to consider controlled trials of drug memory reconsolidation blockade in a treatment setting, with the advantage that a clinically available medication could be used (propranolol or other β-adrenoceptor antagonist) in perhaps only one or few treatment sessions (Taylor et al., 2009; Milton & Everitt, 2010).

Although not alluded to as an explanation, it is possible that the repeated presentations of the drug CS were insufficient to engage the extinction process and that DCS actually enhanced reconsolidation and strengthened the drug memory, the opposite of the intended outcome.

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White's drug memories are understandably so hazy that it's hard to get clarity.

In this study we focus on an approach which targets episodic drug memories to reduce craving, alcohol consumption and relapse rates: Eye Movement Desensitization and Reprocessing (EMDR) [ 15].

The hippocampus and amygdala are structures associated with emotional and drug memories [ 40, 41], and as such, our findings may be explained by memory-related sex differences evoked during the 10-minute smoking cue video.

We then faced a major challenge when seeking to extend the concept of reconsolidation to drug memories that have relevance to addiction because of the marked differences in conditioning history – one or two CS footshock pairings are used to establish conditioned fear and the fear response of freezing is readily measured.

Within this renewed reference context, some of the properties of the components of the remedies to increase mental performance have been studied and validated in experimental models and, to date, these substances are named "smart drugs", "memory enhancing drugs" or "nootropic drugs" (from the Greek root noos for mind and tropein for toward).

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