Sentence examples for drug level in from inspiring English sources

"With drugs that affect mood or behavior such as caffeine, the faster the rise in the drug level in the body, the more intense the response," Benowitz says.

The drug level in heart, gastric and intestine was significantly reduced, which is an indication of reduced side effects.

In an in vivo pharmacokinetic study in fasted Cynomolgus monkeys, the drug level in blood was gradually increased over 4.7 h and high drug concentration was maintained until 24 h, with an elimination half-life of 16.6 h.

To sustain a therapeutic drug level in the retina, VEGF inhibitors have to be delivered frequently, every 4 8 weeks, causing inconvenience for the patients and expenses for the healthcare system.

Therapeutic failures attributed to medical management of cystic echinococcosis (CE) with albendazole (ABZ) have been primarily linked to the poor drug absorption rate resulting in low drug level in plasma and hydatid cysts.

This newly developed approach can be used to predict free drug concentration in diverse tissue compartments for small molecules in toxicology and pharmacology studies, which can be leveraged to optimize the pharmacokinetics drivers of tissue distribution based upon physicochemical and physiological input parameters in an attempt to optimize free drug level in tissue.

Hence, the proposed method allows the therapeutic monitoring of the drug level in plasma Figure 8. Figure 6 Blank plasma in 0.15 M SDS, 0.3% triethylamine, 8% n-propanol all prepared in 0.02 M orthophosphoric acid at pH 4.0.

In these conditions, the low drug level in simulated plasma pH suggests that a triggering mechanism would be required to enhance drug release in situ within the targeted cancer cells in order to spare vital organs and significantly reduce the unwanted systemic side effect.