Sentence examples for drug development programme from inspiring English sources
An integral component of a drug development programme should be an assessment of dose response.
MOE-Dock (Docking software) was used to predict the binding modes of 10 novel and potent 5-substituted amino-2,4-diamino-8-chloropyrimido-[4,5-b]quinolines (compounds I X) as part of our antimalarial drug development programme.
"I don't think we ever doubted the efficacy because the data we were seeing were very consistent from the early days," says Gover. "There have been, without doubt, difficult times for GW, but it is hard to recall a drug development programme that hasn't had delays and setbacks in its history".
I then quantify the advantages of futility stopping in a drug development programme.
Severe delays can ensue, requiring additional investments or, in some cases, trigger the discontinuation of an entire drug development programme.
However, therapeutic margins were only minimal (5 6% over placebo), and this led to the discontinuation of the drug development programme.
Dr. Hotamisligil's research programme crosses the boundaries between disciplines and moves basic and new concepts to human disease and therapeutics and his discoveries have formed the platform for several broadly pursued drug development programmes.
As the failure of several recent Phase III drug development programmes bears witness, the clinical development of "disease-modifying" drugs in Alzheimer's disease has been confronted with challenging methodological difficulties.
