Sentence examples for drug characterisation from inspiring English sources
These input data involved a physicochemical drug characterisation including drug solubility measurements in simulated physiological media, as well as permeability determination.
The aim of the present study was to develop relevant IVIVC models based on mechanistic gastrointestinal simulation (GIS) and artificial neural network (ANN) analysis and to evaluate their applicability and usefulness in biopharmaceutical drug characterisation.
This agrees with the relatively low therapeutic index of doxorubicine in metastatic breast cancer patients [ 40]. 3D-microtissue screening platforms for phenotypic drug characterisation, such as the one presented here, can accelerate the timeline for drug discovery initiatives.
The review is aimed at non-clinical research and development, and will focus on the behaviour and characterisation of drug release from pellets, tablets and capsules, which are the most commonly used drug delivery systems.
Comprehensive characterisation of drug delivery to the lungs is a complex task involving the determination of delivered, deposited and (for systemically-targeted drugs) absorbed dose.
Currently, there is a strong focus on exploring techniques for the characterisation of drug and carrier surface properties that are believed to have an influence on the interparticulate forces in adhesive mixtures.
The distinct merits of the InterMine framework have inspired us to develop TargetMine, an integrated resource for retrieval of target genes and proteins for experimental characterisation and drug discovery.
The advances in molecular and cellular biology have opened new avenues for the characterisation of drug resistant tumours.
This highlights the need for characterisation of drug responses in the zebrafish heart using techniques that assess not only heart rate but also chamber specific wall motion.
Ang-1 showed therapeutic potential for the treatment of sepsis and cardiovascular disorders, but further pharmacological characterisation and drug delivery is required.
Therefore, it could facilitate the systematic characterisation of drug targets, thereby helping to reduce the typically high attrition rates in discovery projects.
