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It is the first drug capable of dissolving tau protein fibres and preventing the formation of neurofibrillary tangles.
To address the need for a drug capable of suppressing premature termination, we identified PTC124-a new chemical entity that selectively induces ribosomal readthrough of premature but not normal termination codons.
Capecitabine is a fluoropyrimidine carbamate that was rationally designed as an oral drug capable of mimicking continuous infusion 5-fluorouracil (5-FU) and delivering 5-FU preferentially to tumour tissue.
Lead researcher Professor Robin Ali explains that the next trial will use a more potent vector and should move the research a vital step closer to the licensing of a drug capable of preserving daytime vision and slowing degeneration – a goal that he believes is attainable "within three or four years".
Because beta-agonists exhibit little or no anti-inflammatory activity, and no current asthma drugs appear effective in deterring airway remodeling, a "multi-tasking" asthma drug capable of inhibiting bronchoconstriction, airway inflammation, and airway remodeling would constitute a novel therapeutic addressing an important, unmet clinical need.
We need to remember that caffeine is a drug, capable of providing us with mental alertness but at higher doses can make us anxious, shaky, and have gastrointestinal problems such as diarrhea.
Similar(36)
Drugs capable of specifically inhibiting prenylation have been developed for use in humans.
CaST aims to develop systematic methods for identifying drugs capable of disrupting master regulator activity.
New drugs capable of restoring the CFTR protein damaged by the most common mutations are required.
If these measures do not provide adequate control, a variety of drugs capable of lowering the cholesterol level are available.
In several cases, his approach has already identified drugs capable of targeting these vulnerabilities, leading to clinical trials to investigate their applicability to human cancer.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com