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Based on re-analysis of the MIST2 trial, we found that both fixed-effects and Mantel-Haenszel dropped a substantial number of patients from the analysis, whereas random-effects and GEE allowed all patients to be included in the analysis.
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Dropping these records from the analysis would mean dropping a substantial percentage of the sample and may lead to misleading conclusions.
The level subsequently dropped to "substantial", indicating "an attack is a strong possibility".
After this initial drop of OLs, a substantial repopulation of NogoA+ cells was observed in rMOG-immunized animals 3 weeks after single, twofold and fourfold lesion induction (Fig. 7b).
(Its continued, large current account surplus is do to earnings on foreign assets, but that, too, is dropping).This shift coincides with a substantial appreciation of the yen.
We had a substantial drop in the first quarter of this year.
The activity then falls off steadily, with a substantial drop after Christmas (in red).
Our workers are facing a substantial drop in their standard of living and continued high unemployment.
A substantial drop to a level of, say, $1.10 by the end of 2011 isn't impossible.
Both manufacturers recorded a substantial drop in orders last year as demand slowed in the aviation market after a short boom.
In this case, though, a pretty modest rate of growth has been associated with a substantial drop in unemployment.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com