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This is followed by a fast drop in tension that is psychologically relieving to both partners because it clears the air of pent-up frustrations and anger.
Given that tension was measured via direct nerve stimulation, the drop in tension output may reflect denervation or a decrease in synaptic efficacy.
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We found that when α5 expression is increased from low to moderate levels, surface tension increases from 5.5 dynes/cm to 10.4 dynes/cm, but further increase in α5 receptor expression paradoxically caused a drop in surface tension back to those measured for low levels of α5 expression.
An increase in Map2 immunostaining was only observed when fibroblasts experienced an acute drop in O₂ tension upon infection.
Surprisingly, the acute drop in oxygen tension did not affect cell proliferation or cell survival and was not synergistic with the blockade of GSK3β and Smad-mediated pathways.
As the oxygen pressure declines, hemoglobin gives up its oxygen with disproportionate rapidity, so that the major fraction of the oxygen can be released with a relatively small drop in oxygen tension.
For example with deionized water there is a drop in surface tension from 71.99 to 70.41 dynes/cm as the temperature is increased from 25 to 35 °C [10].
However, a further increase in α5β1 expression to high (H) and highest (HH) results in a paradoxical drop in surface tension back to 5.5±0.3 dynes/cm and 5.6±0.16 dynes/cm, respectively.
The main advantage of using vectors containing HRE sequence is the induction of transgene expression only upon a drop in oxygen tension.
These findings indicate that a small drop in oxygen tension up-regulates SUR2A in the heart by activating ERK signaling pathway.
These data also reveal that these genes respond to a sudden drop in oxygen tension in addition to the adaptive response previously demonstrated.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com