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This drop in probe quality, in addition to a greater focus on low-frequency and rare variants (those with minor allele frequencies 0.5 5% and <0.5%, respectively; The 1000 Genomes Project Consortium, 2010) presents many problems for existing genotype-calling algorithms.
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One week after DT administration, the same imaging protocol revealed a significant drop in the probe accumulation in all male mice (p < 0.01) and most female mice (p < 0.05; ESM Figs 5 and 6).
I found the built-in probe thermometer accurate.
The drop in counts as the probe is angulated whilst over a hot-spot can confirm location.
The drop in PO2 at the probe tip was measured over 20 s and compared to precalculated theoretical profiles to determine the rate of oxygen consumption of the muscle (mVO2).
By using a thresholding algorithm that calculates the percent drop in intensity of the probes in the HiLo image relative to the uniform image, we eliminated almost all probe data 0.5 μm or further from the image plane.
Even though both the 0.5 μg and 0.1 μg comparisons are 4 × 4 comparisons, there is a 50% drop in the number of significant probe sets as compared to the 10 μg samples.
Dick Olver, BAE's chairman, acknowledged as much on May 7th when he called for a review of the SFO's evidence a remarkable change of heart from a firm that had previously lobbied the government in secret to drop the probe.
The initial drop in absorption is due to probing state filling in SWNTs, a trend obvious in Fig. 5.
The EGFR exon 19 deletion probe resulted in a drop in endpoint fluorescence, while in a wild-type sample, both probes gave a signal.
Francisco originally contested the challenge to the SEC but switched sides at the end of November — exactly a month after the first charges dropped in Mueller's probe.
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