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Moreover, the analysis of polymorphism and divergence at coding regions constitutes a powerful approach to detect the action of recurrent positive selection driving to fixation amino acid changes after relatively recent speciation events.
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In the classical selective sweep model, positive selection acts on a new allele that arises by mutation, driving it to fixation within a population or species (Maynard Smith and Haigh 1974).
A "selective sweep" is the process of natural selection driving a mutation to fixation.
In other words, salmon domestication may not involve classical selective sweeps with strong selection on loci with large effects driving beneficial alleles to fixation, but instead subtle shifts in allele frequencies in QTLs underlying adaptation to the hatchery environment.
Episodes of gBGC in a genomic region could produce an association between W→S substitutions and substitution density (BDS) by driving W→S mutations to fixation in recombination hotspots.
Specifically, under the assumption that synonymous changes are neutral, ω < 1 is regarded as evidence of purifying selection acting on nonsynonymous mutations, ω = 1 reflects neutral evolution, and ω > 1 can be viewed as support for past episodes of positive selection driving nonsynonymous mutations to fixation (Li 1997; Nei and Kumar 2000; Yang 2006).
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