Sentence examples for driving the progression of from inspiring English sources

Among others changes in the enteric microbiome and an increased intestinal permeability contribute to an overflow of bacterial metabolites into the liver via the portal vein driving the progression of NAFLD.

However, the initiating factors causing microvascular changes are the primary targets driving the progression of sporadic SVD need to be better understood.

Leveraging advancements in next-generation sequencing technologies, large-scale efforts have cataloged the somatic mutational events driving the progression of cancer [ 1- 3].

There is no question that cigarette smoking is the dominant risk factor for COPD and is the most important factor driving the progression of airflow obstruction.

All these point to the de novo intratumoural synthesis of androgens that could be critical to driving the progression of castration-resistant tumours.

37– 39 However, future studies using cell type-specific deletion of IL-17RA will be essential for determining the critical IL-17RA-expressing cell type(s) important in driving the progression of NAFL to NASH.

Several studies showed that TAZ amplification existed in lung cancer, driving the progression and metastasis of lung tumor-propagating cells [ 15] and significantly correlated with the prognosis of patients [ 11].

It is possible that loss of PKD1 expression and the resulting change in the expression of MMPs is part of the switch driving the progression from a benign to an invasive, malignant tumour.

The naïve approach of considering all candidates from all detection tools quickly overwhelms the capacity of experimental validation procedures, and highlights the need to focus on a reduced number of select biologically relevant fusions driving the oncogenic progression of disease.

Thus, viral persistence is the driving force behind the progression of the disease [ 29].

Recent observations have provided evidence that diastolic rather than systolic dysfunction is the driving factor in the progression of AHFS (Gandhi et al. 2001).