Successful implant integration into the surrounding tissue is highly dependent on the crucial role of blood supply in driving bone repair and development.
However, in this model, the main cell type driving the repair process may not be the chondrocyte per se, but is perhaps a mesenchymal stem cell population, resident within the subchondral bone or invading blood vessels, which may not be as responsive to BMP-7 treatment.
To guide therapeutic intervention, we need a better understanding of the fundamental mechanisms driving tissue repair; this will require complementary wound-healing studies in several model organisms.
Apparently, mechanisms similar to the ones driving DNA repair induction in this study were causing the suppression of the DNA double strand break levels below the background one reported for mice chronically exposed to very low dose rate gamma-irradiation (Osipov et al. 2013).
She was small in stature, but always dressed up, even when she was at a construction site, driving or repairing a test boring rig, hard hat on her head.
Florida Power & Light trucks were driving around to repair outages.
TLR signaling is paramount in driving intestinal tissue repair and regeneration (19), as evidenced by germ-free mice and mice deficient in MyD88 having an impaired ability to repair intestinal injury (20).
Damage directly in the driver's line of sight can interfere with driving even after repair.
Mr. Kushner is the de facto lead mechanic for the family's stable, while Amy, his wife, fits the children into their neck braces, chest protectors, helmets and driving suits, and repairs damaged egos or hurt feelings as needed.
And because the car inspection process tells Mota any problems with a car that's being purchased, it can offer buyers coupons for any repairs they might need — again driving more leads to repair shops.
