Sentence examples for driving progression from inspiring English sources
The Wang Laboratory is primarily interested in understanding the epigenetic mechanisms driving progression of hormone-dependent cancers.
Growth inhibition was indicated by an induction of p53 target genes, p21 and GADD45A, and decreased expression of genes driving progression through various phases of the cell cycle.
This is a valuable feature given that genetic and epigenetic alterations accumulated by the mature gland likely play a role in driving progression of prostate cancer in humans.
Growth inhibition was indicated by an induction of p53 target gene p21 and decreased expression of genes driving progression through phases of the cell cycle, such as CDC2 and CDC20.
The molecular mechanisms driving progression, grade, and stage are overlapping.
Gene amplification has been postulated as a mechanism driving progression in many carcinomas.
Some element of inflammation that drives plaque formation in coronary disease is also driving cancer progression.
In light of recent evidence implicating IL-8 in driving disease progression, it is possible that elevated levels of IL-8 are responsible for selectively driving disease progression in ER-negative/ triple-negative tumors compared with ER-positive tumors; however, this remains to be determined.
Thus, the complex biological mechanisms driving tumor progression cannot easily be recreated in the laboratory.
The role of the bone marrow microenvironment (BMM) in driving disease progression is widely recognized, with chemokine receptors (CXCR4), adhesion molecules, signal transduction pathways and hypoxia-related proteins playing a role [18,19,20,21,22,23,24,25,26].
