The transformation gives an approximated version of both pattern and driving episode, eliminating noise residing in the original patterns and/or driving episodes in the process.
The focus of this chapter is to review aberrant DNA methylation and hydroxymethylation patterns in cancer, mutations in epigenetic regulators involved in DNA methylation maintenance fidelity, and the driving events in the process of DNA methylation in tumorigenesis.
This water is then let back into the sea, driving turbines in the process.
The connection between ecomorphological divergence and speciation is a central issue in adaptive radiation, and the role of competition in driving the process has long been suggested (Fryer, 1959; Coulter, 1994).
It is hard to credit any one researcher with the discovery, though key findings were made by the Dutchman Jan Ingenhousz in 1779, who revealed the crucial role of sunlight in driving the process.
Our current understanding of MSF expression and functionality during breast cancer progression is summarized in Fig. 2. We originally speculated that 'foetal-like' fibroblasts were associated with breast and other types of cancer, and that the resultant perturbations in signalling between stroma and epithelium played an important role in driving the process of tumour progression [ 4, 5].
In an interview last week, Stuart Eizenstat, co-chair of the Transatlantic Business Council – instrumental in driving the process – was asked if companies whose products had been banned by regulators would be able to sue [see footnote].
Two different methods of designing a control system which minimizes the overall operating time used in driving the process from a default mode to one of the nominal modes, respecting the constraints on the continuous variables, are presented.
A reconstruction of the administration's Iraq policy review, based on more than a dozen interviews with senior advisers, Bush associates, lawmakers and national security officials, reveals a president taking the lead in driving the process toward one more effort at victory -- despite doubts along the way from his own military commanders, lawmakers and the public at large.
In this study we have explored the role of cell migration between tissue surfaces in driving the process of integration.
