Sentence examples similar to driving force behind alteration from inspiring English sources

Deceleration of epidermal aging in an autophagy mutant suggests that autophagy is a driving force behind age-related alterations in the fly epidermis, in contrast to its protective role in other tissues.

Student applicants are also a driving force behind the change.

Loss of chromosome 9p has been reported as an early and frequent event in oral tumorigenesis, with selection for the loss of tumor suppressor CDKN2A (at 9p21.3) believed to be the driving force behind the emergence of this alteration 12, 38.

Although the premise of our Discussion is that the driving force behind 8p rearrangements is selection for the alteration of cancer genes, the same pattern of rearrangements might be observed if the driving force was the mechanism of breakage e.g the presence of fragile sites on 8p.

UC is also characterized by a strong association between tumor stage/grade and karyotypic complexity, indicating that progressive accumulation of genetic alterations is the driving force behind multi-step bladder carcinogenesis [ 2].

Notwithstanding, endogenous miR dysregulation may be reflective of underlying genetic alterations rather than the driving force behind observed effects.

These findings indicate that next to mutational activation of the Wnt pathway, gene expression alterations should be considered also as driving force behind Wnt activation in GEJ adenocarcinomas.

Alterations in enhancer usage and activity are a driving force behind oncogenesis and thus have broad medical applications.

A major driving force behind the progression from localised prostate cancer to advanced disease to CRPC is mediated by androgens and alterations in the androgen pathway that sustain the disease.

But he was hardly the driving force behind them.

Mr. Siren has been the driving force behind the initiative.