One prediction from these data is that, in contrast to exclusively driving tumor initiation as known to do in colorectal cancer for example, APC loss would actually prevent primary tumor invasion or metastasis to a distant site.
The correlations with oceanographic connectivity remained significant when the DE-RUGEN site was removed (60 loci: r = 0.386, P = 0.010; 59 loci: r = 0.342, P = 0.026, Her14 r = 0.657, P = 0.002; Table 2), indicating that connectivity at DE-RUGEN was important but not driving the result exclusively.
Of the 14 GO categories enriched during the transition from 4 to 24-h amastigotes, those related to microtubules and protein complexes were specific to upregulated genes with many copies of β-tubulin, the primary component of microtubules, almost exclusively driving the GO analysis results.
(Weight is most important in stop-and-go driving. In almost exclusively highway driving, it matters little: once the car is up to speed, it need only push air out of the way).
A more sensible policy would be based exclusively on gas taxes: they directly confront motorists with increased costs of driving, which not only has an immediate influence in reducing mileage, but also encourages the purchase of more efficient cars.
The Americans were driving along a road used exclusively by the American military and reconstruction teams when a bomb, which local Iraqi security officials described as an improvised explosive device, went off.
Recording of such parameters can be particularly useful especially in cases where driving behavior is not approached exclusively in speed terms.
This aim has been facilitated by the implementation of the Cre/ loxP recombination system in mice and the characterization of powerful cell type specific promoters driving Cre-mediated gene deletion exclusively in the target cell of interest [ 130].
After passing a law in 2014 requiring citizens to have a photo identification in order to vote, Alabama is now closing 31 driving license offices that are almost exclusively located in African-American communities.
