Sentence examples for drives translation from inspiring English sources

This diagnostic problem is compounded by our relatively poor understanding of the complex molecular machinery that drives translation in mitochondria.

The majority of translation in eukaryotes is dependent on eIF4E binding to 7mG, which drives translation initiation by recruiting the 40S ribosomal subunit [ 3, 24].

Of note, in cells where the eIF4E-binding protein 4E-BP1 is limiting, eIF4E overexpression also drives translation initiation in a rapamycin-resistant manner (Dilling et al, 2002).

S6K1 drives translation of 5′TOP (terminal oligopyrimidine tract) mRNAs, and 4E-BP1 inhibithethe mRNA cap-binding protein elF4E (Schmelzle and Hall, 2000).

For example, although the cytoplasmic hnRNP A1 destabilizes mRNA of cIAP1 in UV-irradiated cells and suppresses internal ribosome entry site (IRES -mediated translation of X chromosome-linked IAP (XIAP) and B-cell lymphoma-extra large (Bcl-xL) during hypertonic shock, the same cytoplasmic accumulation drives translation of human rhinovirus (HRV) RNA and is required for efficient infection.

Aminoacyl-tRNA synthetases (aaRSs) are indispensable components of all cellular protein translational machineries, and in humans they drive translation in both cytoplasm and mitochondria.

EMCV IRES-driven translation does not need eIF4E but requires the rest translation initiation factors (Jackson et al., 2010).

Electrically driven translation stages are used to adjust the position of the measurement point on the object.

According to a recent report, PABP cleavage by 3Cpro inhibits PV IRES-driven translation [60].

In agreement with this data, 2Apro partially restores PV IRES-driven translation in HeLa extracts treated with 3Cpro [60].

Mammalian target of rapamycin (mTOR) plays a central role in regulating AKT driven translation initiation by regulating S6K1 and 4EBP1 activity [31].