Sentence examples for drives alterations from inspiring English sources

The coupling of the suicidal binding of ATP to large-scale conformational change drives alterations in molecular organization that are necessary to hold the sliding clamp open and position it on the DNA.

These data lend further weight to the hypothesis that HIV infection drives alterations in bone phenotype and provide a potential mechanism for the evolution of this complication of HIV1 infection.

It has been demonstrated that neoplastic breast stroma drives alteration in gene expression as compared with normal tissue (Leygue et al, 1998).

Oye is not alone in calling for government agencies, scientists, and the general public to figure out how to regulate the release of mosquitoes and other organisms with gene drive alterations.

The development of central drive alterations was more pronounced in the KE muscle group than in PF and there was a significant correlation between %VA changes for KE and PF (R = 0.47; P<0.47).

This could drive alterations in mitochondrial genome sequence in infected species.

Although local trauma to mechanoreceptors in the neck cannot be excluded, our findings favour centrally driven alterations in motor control due to long-standing pain.

Catalytic ATPases are involved in the energy driven alterations of nucleosome positioning and DNA-histone associations during the process of chromatin remodeling [[ 20], table 1].

The PGC1 coactivators play essential roles in BAT differentiation, mitochondrial biogenesis, and thermogenesis [ 58], so increased expression of PGC1 could drive alterations in WAT morphology and UCP1 gene expression towards a 'brown fat' phenotype in Vgf C 57 -/- mice.

The overarching paradigm of this work is that genetically driven alterations in the pattern of DNAm of white blood cells can result in functional deficits in the normal functioning of immune system that modify disease susceptibility.

In addition, the more pronounced damage to basal cochlear HCs that are high frequency-tuned, compared to apical HCs that are low frequency-tuned, is also consistent with mechanically driven alterations of the junctions between HCs and their SCs in Vezt fl/fl:PrestinCre mice (see Ashmore, 2008).