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However, data from our agglomerated MO NPs suggests that the elemental composition and dissolution potential are major drivers of toxicity.
A key component for the identification of hazard drivers in complex mixture exposure is the EDA approach, where combinations of non-target/target screening [31] with bioanalytical tools can be applied in different tiers to identify drivers of toxicity or in combination with toxicity information or hazardous properties of encountered substances [35, 42].
Trends for zinc, barium, potassium, and copper were noted, although the authors acknowledge that these may be markers rather than drivers of toxicity.
Recent findings suggest a refinement to this hypothesis: it may be that the primary drivers of toxicity are metastable non-fibrillar species known as soluble oligomers (Glabe, 2008; Benilova et al., 2012; Krishnan et al., 2012).
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As a result, the illustration has focused on organizing of the exposures into the four Groups and identifying which chemicals are the drivers of mixture toxicity for Group IIIB.
Future research should endeavor to incorporate multivariate analyses with more complex study designs to better delineate the putative drivers of vascular toxicity.
Finally, we sought to exploit our understanding of sex-associated transcriptional profiles to identify candidate drivers of dioxin toxicities.
Several reports have compared the toxicities of different PM samples and, using associative statistical analysis, identified putative drivers of the toxic responses.
The worry of toxicity is hugely overblown.
They speak of "toxicity" and set out for Yukon.
The overwhelming majority of studies it reviewed showed no evidence of toxicity.
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