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Nevertheless, through the online analysis, shown in Fig. 27, it is possible to note that reckless drivers' events—such as sudden lane changes, abrupt accelerations/decelerations, and jerks generated more uncomfortable feelings for passengers once more than 75% of the outliers were out of the comfort range.
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We performed large-scale genome sequencing analyses on BTCs to investigate their somatic and germline driver events and characterize their genomic landscape.
Uncovering and dissecting true driver events in MM might provide rational for new potential targets and therapeutic option in the disease.
The new paradigm of mutations in chromatin-modifying genes as driver events in the development of cancers has proved challenging to resolve the complex influences over disease phenotypes.
The classical myeloproliferative neoplasms (MPN) are comparatively uncommon in children and display a degree of mutational naivety if considering the high frequency of known MPN driver events observed in the corresponding adult diseases.
These findings coupled with the diverse (sub clonal evolution trajectory followed by CLL cells, at least in treated patients, alludes to their role as major subclonal driver events for disease progression.
Rather than pumping potential financial services customers with alerts via its app, Grab plans to take a community-driven approach and promote the availability of services using its driver events, its network of agents and other offline means.
Of course, the distinction between driver events and biological neutral passenger changes is difficult to achieve definitively.
We considered recently discovered Pan-cancer driver events (Zack et al., 2013) as the known driver events for generating lengths and amplitude of driver SCNAs.
Hypermethylation of specific genes might then account for passenger methylation events rather than for driver events.
PTPRB inhibits angiogenesis, and inactivating mutations of PTPRB are considered driver events in angiosarcoma.
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CEO of Professional Science Editing for Scientists @ prosciediting.com