Sentence examples for driver pathway from inspiring English sources

The classical thalamo-cortical pathway that terminates in the middle cortical layers is considered to be a driver pathway, and the reciprocal cortico-thalamic pathway emanating from cortical layer VI is thought to be modulatory [8], [9], [12], [15].

Hence, our method can seek out driver pathway.

So, we emphasize that assumption of mutual exclusivity occurs only in the same driver pathway.

The fourth direct driver pathway arose from the other three drivers.

In bioinformatics, it is important to detect mutated driver pathway in cancer cells.

Nevertheless, we study the D=P model to consider the limits of driver pathway identification.

Finally, we draw our conclusions in Section 4. Identifying driver pathway is extremely difficult.

Thus under the D=P model we identify the driver pathway by maximizing W(M).

Although the proposed method can find mutated driver pathway without relying on prior knowledge, we should note that the assumption of high exclusivity and high coverage is too strict for selecting the driver pathway.

Vandin, F., Upfal, E. & Raphael, B. J. De novo discovery of mutated driver pathways in cancer.

The identification of mutated driver genes and driver pathways from these data is a significant challenge.