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Activated/injured endothelium is a key driver of platelet activation.
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The growing complexity of platelet aggregation.
Nieuwenhuis, H.K., Sakariassen, K.S., Houdijk, W.P.M., Nievelstein, P.F.E.M. & Sixma, J.J. Deficiency of platelet membrane glycoprotein Ia associated with a decreased platelet adhesion to subendothelium: A defect in platelet spreading.
contributed to the study of plasma coagulation factors, platelet aggregation assays and flow cytometric analysis of platelet membrane glycoproteins in platelet-rich plasma.
Platelet localized COX-1 enzyme produces precursors for the synthesis of thromboxane, a potent inducer of platelet aggregation (Schafer, 1995).
Savage, B., Cattaneo, M. & Ruggeri, Z.M. Mechanisms of platelet aggregation.
Phosphoinositide 3-kinases and the regulation of platelet function.
Kulkarni, S. et al. A revised model of platelet aggregation.
Methods for the measurement of platelet function.
Evaluation of platelet function by flow cytometry.
Mechanisms and implications of platelet discoid shape.
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