Sentence examples for driver of insulin from inspiring English sources
Obesity is the major driver of insulin resistance and T2DM.
It is clear from Figure 5a that purine metabolism is the primary driver of insulin resistance.
Although truncal fat is an important driver of insulin resistance [ 18], and adjustment for WHR has been shown, for example, to influence the relationship of HOMA-index with left ventricular mass in people without diabetes [ 19], once diabetes is present, it is possible that excess truncal fat no longer predicts future CVD events.
The insulin receptor acts as the key driver for insulin action but also clearance.
The results were interpreted as evidence that oscillations in islet [Ca2+]i are an important driver of in vivo plasma insulin oscillations [20].
The quantity of adipose tissue is an important driver of adipose tissue dysfunction, insulin resistance and cardiovascular disease.
Although the main driver of T2D is peripheral insulin resistance, compromised beta cell function is believed to be an important (genetic) factor in the pathogenesis of T2D.
Subsequent guidelines and expert consensus have recognised the importance of atherogenic dyslipidaemia as a key driver of CV risk in insulin-resistant states, even if LDL cholesterol levels are well controlled [ 8- 12].
Diabetes severity may be a prime driver of breast cancer risk, and insulin is always used at a late stage of diabetes when pancreatic β cells are exhausted and most OAD fail to adequately control blood glucose.
The aims of the present study were (1) to examine the effects of weight loss induced by hypocaloric diet (HCD) on insulin clearance, SNS activity and vascular function and (2) to delineate the pathophysiological drivers of improvement in insulin clearance following lifestyle intervention.
27 As insulin and insulin secretagogue (eg, sulfonylurea) treatment is the main driver for hypoglycemia in combination therapy, a lower dose of insulin or the insulin secretagogue may be necessary in comedication with canagliflozin.
