Sentence examples for driver functions in from inspiring English sources

Among genes with tumor-specific retentions, genes with known driver functions in cancer were rediscovered, including EGFR, ROS1, ATM and KDR.

In conclusion, the SRF-VP16 iHep mouse model, which is shown to display, in part, gene expression profiles elicited upon combined oncogenic Ras/MAPK and Rho/actin signaling, identifies SRF target genes to fulfill oncogenic driver functions in HCC.

The widespread incidence of this genetic alteration, the high extent of RAF catalytic hyperactivation produced by this amino acid-specific mutation and its strong transforming properties in vitro and in vivo are powerful indicators of its driver function in melanomagenesis (Gray-Schopfer et al, 2007).

Research has shown that drivers function in a state of current and immediate knowledge of the driving environment.

Ventricular driver functions are not readily measured in the ICU, but can clearly indicate the development of pulmonary embolism (PE) otherwise difficult to diagnose.

The variation in shape and difference in phase of the modeled outputs compared with the measured waveforms (Figures 3 and 4) are due to the lumped parameter nature of the model and errors in the approximated driver functions (driL and driR) used to describe the myocardial contraction.

The variation in shape and difference in phase of the modeled outputs compared with the measured waveforms are due to the lumped parameter nature of the model and errors in the approximated driver functions (driL and driR) used to describe the myocardial contraction.

Take some time to understand the main driver functions train and classify and all of the comments in the file.

Nf2+/− mice on a C57Bl/6J genetic background were used for several reasons including the observation that tumor that develop in Nf2+/− mice exposed to asbestos show common genomic alterations with human mesothelioma and loss of NF2 function has a driver role in mesothelioma development [13,14,15,16], and C57Bl/6J mice being widely used in functional studies.

Codes captured the type of driver, how and when it was introduced, at what level of the health system the driver functioned and challenges faced in implementation.

The recent report of a recurrent gene fusion of UBR5 on 8q22.3 and ZNF423 on 16q12.1 (UBR5- ZNF423) in 8 % of EBV-associated primary nasopharyngeal carcinomas suggests a driver function of this gene fusion in a subset of nasopharyngeal cancers [ 163].