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The primary end point was 1-year target lesion failure, defined as cardiac death, target vessel myocardial infarction, or clinically driven target lesion revascularization.
These observations suggest that pharmacologically driven "target identification" plays an important role in the continued development of new therapeutic agents, and underscores the need for more research into the biologic basis for different subtypes of lymphoma.
The primary efficacy end point was primary patency, defined as freedom from restenosis or clinically driven target lesion revascularization at 12 months.
As a secondary analysis, clinically driven target lesion revascularization was analyzed by the Kaplan-Meier method during the 12-month follow-up period.
The DCB-treated patients demonstrated lower rates of clinically driven target lesion revascularization versus PTA-treated patients through 12 months (2.4% versus 20.6%; P<0.001; Figure 2).
The rate of clinically driven target lesion revascularization was 2.4% in the DCB arm in comparison with 20.6% in the PTA arm (P<0.001).
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Year on year, through below-inflation pay rises, market-based reforms and centrally driven targets, public sector workers have been demoralised, undermined and devalued.
P1f mice were generated using the Piezo1tm1a KOMP Wtsi Knockout First, promoter driven targeting construct from KOMP.
Therefore, our Tbx4-lung enhancer driven targeting driver line has the potential to be used in the study of adult lung diseases, such as asthma, emphysema and interstitial pulmonary fibrosis.
Our results demonstrated that the artificially-designed CAG promoter is a potent promoter that effectively drives target gene expression in IUE system.
A set of driving electrodes, marked as E-drive in Figs. 2 and 3, offers an electric field in the desired direction to drive target particles in the microchannel.
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