The distinction between definite and probable is to some extent driven by the severity of events, with less severe events possibly not resulting in a secondary referral.
Our strategy tested whether associations were driven by the most severe individuals.
In generation of the heatmaps, genes included were largely driven by the NV-C severe group, requiring a minimum q-value of 0.05 across all contrasts included.
In the absence of TSA, wings overexpressing Gro driven by the MS1096-Gal4 driver show 26% severe blistering, 11% moderate blistering, 47% mild blistering and 16% no blistering (Fig. 4E, purple bars).
The results were to a large extent driven by the relative efficacy in preventing severe exacerbations.
It implied the relationship between Aβ loads and cognition in MDD patients was driven by the subjects with moderate-to-severe treatment resistance who had relatively higher Aβ accumulation and lower MMSE score, compared to the patients with mild treatment resistance.
In terms of wealth and assets, the recent deterioration nationally, driven by the economic collapse, has been most severe among blacks and Hispanics, although whites have certainly not been exempt.
Despite the general medical ward's importance in the spectrum of sepsis care, few studies of severe sepsis have examined functional outcomes of patients initially cared for on the general medical ward, and it is possible that the adverse outcomes reported after severe sepsis are driven by the subset of ICU patients.
Table 7 The natural history of 3MCC has been driven by the clinical ascertainment of patients presenting with severe acute episodes.
Consistent with our hUCP2 studies, two out of five independent UAS -mucp1 lines (UAS -mucp1A and UAS -mucp1B) with the highest mitochondrial protein expression (data not shown) also engender the most severe developmental lethality when driven by the ubiquitous actin-Gal4 driver (data not shown) [ 6].
