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In contrast, the BASP1 mutant derivative K6A K9A did not drive repression of amphiregulin expression.
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Several models have been proposed to explain the crosstalk between NRs and general transcription factors (TF) to drive transcriptional repression.
Thus, p300 is both necessary and sufficient to drive the repression of miR-142 in the absence of hypertrophic extracellular signals or MAPK activation.
Viewed in this context, one would predict that polycomb domain formation would not directly drive gene repression, but may instead function to limit stochastic or inappropriate reactivation of genes that have already been transcriptionally silenced.
Driven between repression and release, she embodies Baroque opera.
Thank you for submitting your work entitled "Resection drives transcriptional repression around a DNA double-strand break in Saccharomyces cerevisiae" for peer review at eLife.
Disruption wars in Africa, Iraq and Afghanistan and repression drove some people from their homes.
Mr Turabi's charismatic leadership provided the ideology and politics.Fierce repression drove other political parties underground or into exile, until Mr Turabi felt sufficiently powerful to ease up, and allow a restricted form of democracy, including a national parliament.
Haitians have been migrating to the United States since even before their nation became independent in 1804, but the bulk came in waves driven by political repression and economic uncertainty, through the 1980s and 1990s.
We found that the level of adh1+ mRNA was a little lower in hip3-1 cells than in wild-type cells, whereas the level of SPCC663.14c+ mRNA was approximately 1.4-fold higher in hip3-1 cells than in wild-type cells (Fig. 5), suggesting that Hip3-1 produces a defect in transcriptional repression driven by the meiosis-specific gene promoters.
Krueppel-Associated Box (KRAB -associated protein 1 (KRAB -associatedcriprotein regulatory factor that drives the epigenetic repression of many different loci in mammalian genomes.
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