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The elevation of the inflammatory response itself does not drive elimination of healthy neurons (Figs 3 and 4) and macrophage infiltration into the CNS is not seen (Fig. 2).
Next, we hypothesized that "Darwinian-like" interactions between impaired and newly formed tissues may trigger cell death, since negative selection can drive elimination of less fit cells during development or carcinogenesis [ 1 11].
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The resulting enzyme constructs drive specific elimination of selected DNA targets in vivo and display shifted specificities of DNA binding and cleavage in vitro.
This drive toward elimination has been used as an argument in favor of pre-erythrocytic and transmission blocking vaccines [TBV, or Vaccines Interrupting Malaria Transmission (VIMT)], and against asexual blood-stage vaccines (BSV).
Gary Cowger, the president of G.M.'s North American operations, said: "The improvement in quality basically drives the elimination of waste.
Antagonistic pleiotropy results from the futile competition between different sigma factors associated with the RNA polymerase, and drives the elimination of RpoS (or σS) in environments requiring high levels of transcription that is dependent on RpoD (or σD or σ70).
Therefore, it is not starvation per se that drives micronuclear elimination in response to colchicine.
This has important implications for late-stage candidate selection and assessing how they can support the drive for malaria elimination.
As the drive towards malaria elimination intensifies, the question arises as to the added benefit of identifying and treating low-density infections in order to interrupt transmission.
"The decisions these people are making in their lives help bring the viewer along," he said, "giving it the drive of an elimination show, keeping the action and the drama propelling it forward".
The momentum for disarmament, reflected in Obama's speech with Brown's reluctant accord, began two years ago, as Henry Kissinger and his colleagues began a drive for the elimination of nuclear weapons.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com