Sentence examples for drive alterations in from inspiring English sources

This could drive alterations in mitochondrial genome sequence in infected species.

The PGC1 coactivators play essential roles in BAT differentiation, mitochondrial biogenesis, and thermogenesis [ 58], so increased expression of PGC1 could drive alterations in WAT morphology and UCP1 gene expression towards a 'brown fat' phenotype in Vgf C 57 -/- mice.

In mechanistic terms, the GHKL+S5 modules of both topoisomerases and MutLs constitute engines that use ATP hydrolysis to drive alterations in protein-protein interactions in the complexes they are part of, as well as mediate large movements of DNA strands – topoisomerization and looping of DNA between the epigenetic marks and mismatch sites [ 17].

Kusminski, C. M. et al. MitoNEET-driven alterations in adipocyte mitochondrial activity reveal a crucial adaptive process that preserves insulin sensitivity in obesity.

Although local trauma to mechanoreceptors in the neck cannot be excluded, our findings favour centrally driven alterations in motor control due to long-standing pain.

The overarching paradigm of this work is that genetically driven alterations in the pattern of DNAm of white blood cells can result in functional deficits in the normal functioning of immune system that modify disease susceptibility.

The coupling of the suicidal binding of ATP to large-scale conformational change drives alterations in molecular organization that are necessary to hold the sliding clamp open and position it on the DNA.

These data lend further weight to the hypothesis that HIV infection drives alterations in bone phenotype and provide a potential mechanism for the evolution of this complication of HIV1 infection.

One compelling idea is that HIF-1 driven alteration in metabolism in Aβ resistant cells confers a selective advantage for survival in the hostile environment of the AD brain [14], [49].

These patterns indicate that this pain model resulted in SNL-specific changes in miRNA expression levels, suggestive of an SNL- injury driven alteration in the underlying molecular biology of the DRGs.

It has been demonstrated that neoplastic breast stroma drives alteration in gene expression as compared with normal tissue (Leygue et al, 1998).