Sentence examples for drive alterations from inspiring English sources

Oye is not alone in calling for government agencies, scientists, and the general public to figure out how to regulate the release of mosquitoes and other organisms with gene drive alterations.

The development of central drive alterations was more pronounced in the KE muscle group than in PF and there was a significant correlation between %VA changes for KE and PF (R = 0.47; P<0.47).

This could drive alterations in mitochondrial genome sequence in infected species.

The PGC1 coactivators play essential roles in BAT differentiation, mitochondrial biogenesis, and thermogenesis [ 58], so increased expression of PGC1 could drive alterations in WAT morphology and UCP1 gene expression towards a 'brown fat' phenotype in Vgf C 57 -/- mice.

In mechanistic terms, the GHKL+S5 modules of both topoisomerases and MutLs constitute engines that use ATP hydrolysis to drive alterations in protein-protein interactions in the complexes they are part of, as well as mediate large movements of DNA strands – topoisomerization and looping of DNA between the epigenetic marks and mismatch sites [ 17].

The observed change in the Atg14L levels alone may not be sufficient to drive alteration of autophagy in particular in the context of AMD3100.

Although local trauma to mechanoreceptors in the neck cannot be excluded, our findings favour centrally driven alterations in motor control due to long-standing pain.

Catalytic ATPases are involved in the energy driven alterations of nucleosome positioning and DNA-histone associations during the process of chromatin remodeling [[ 20], table 1].

The coupling of the suicidal binding of ATP to large-scale conformational change drives alterations in molecular organization that are necessary to hold the sliding clamp open and position it on the DNA.

The overarching paradigm of this work is that genetically driven alterations in the pattern of DNAm of white blood cells can result in functional deficits in the normal functioning of immune system that modify disease susceptibility.

These data lend further weight to the hypothesis that HIV infection drives alterations in bone phenotype and provide a potential mechanism for the evolution of this complication of HIV1 infection.