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Although screening for prostate cancer with prostate-specific antigen (PSA) or digital rectal exam (DRE) is commonly done, evidence is currently lacking to show a benefit of such testing on survival.
The "per rectal" (PR) or "digital rectal exam" (DRE) can be a very difficult diagnostic test for even the most skilled operator to discern pathological versus normal; we propose this is especially the case in the emergency department patient population.
To put our results in perspective, we compared them to three other screening tools commonly used in clinical practice: the prostate-specific antigen (PSA) and digital rectal exam (DRE) for prostate cancer and mammography for breast cancer.
Urine was collected post attentive digital rectal exam (DRE) and prior to needle biopsy.
Abbreviations: PSA, prostate specific antigen; ng/mL, Nanogram per milliliter; DRE, Digital rectal exam.
Prostate cancer screening is traditionally based on digital rectal exam (DRE) and prostate specific antigen (PSA) level measurement [ 2].
Abbreviations: CCI, Charlson Comorbidity Index; PSA, prostate specific antigen; ng/mL, nanogram per milliliter; DRE, digital rectal exam.
The predictive accuracy of the model was compared to a "base" model of PSA, age and digital rectal exam (DRE).
DRE: Digital rectal exam; NCI National Cancer Institutee; ACS: American Cancer Society; PNRP: Patient Navigation Research Program VA Veterans Affairs PSAProstatespecificecific antigen; IRB: Institutional Review Board; TRUS: Transrectal ultrasound; HR: Hazard ratio; HR: Hazard ratio; CCI: Charlson Comorbidity Index.
In 1994, the FDA approved the use of the PSA test in conjunction with a digital rectal exam (DRE) to test asymptomatic men for prostate cancer.
aStage T2 category refers to tumors that can be felt during a digital rectal exam (DRE) or observed with imaging, but is still confined to the prostate.
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