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In 25 paired blood samples assayed for DNA repair capacity (DRC) by the HCR assay, the DRC values of frozen whole blood (mean +/- SD, 11.59 +/- 3.07) were similar to those of frozen isolated lymphocytes (11.08 +/- 3.50).
This method produced a range of DRC values from nearly 0 to 19% DRC.
The correlation between the paired DRC values was 0.77 (P < 0.001).
Grossman and Wei [ 5] demonstrated that, at this precision, our assay can distinguish both intra- and inter-assay variation by being able to maintain the ranks of DRC values in samples measured in triplicate from multiple patients.
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With fully saturated dose response curves (DRCs), meaningful D0 values were assumed for De estimation.
However, a higher specificity and sensitivity would increase the value of DRC as a detector of BC.
Because any given specific value of DRC level is associated with a quantitative BC risk estimate, DRC has the potential to be a biomarker to rule out BC risk in low-prevalence or low-risk populations or confirm its presence in high-prevalence or high-risk populations.
Leave any bitrate, sample rate and DRC settings at their default values.
Peer Reviewed Cite this article as: Kayembe P, Babazadeh S, Dikamba N, Akilimali P, Hernandez J, Binanga A, et al. Family planning supply environment in Kinshasa, DRC: survey findings and their value in advancing family planning programming.
Though it would be a simpler solution to stop our suppliers from sourcing from countries where challenges exist such as the DRC, doing so goes against our core value of leaving the world better than we found it.
Agriculture employs most of the labor in DRC and produces the largest percentage of total value added.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com