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There are two major drawbacks of this method.
The virtues and drawbacks of this method are summarised.
The merits and drawbacks of this method are also discussed.
The primary drawbacks of this method are high computational complexity and reduced throughput.
This cleavage step is thus one of the drawbacks of this method.
One of the drawbacks of this method is that hydrazine hydrate is highly toxic and explosive in nature.
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In this article we present the drawback of this method.
However, the major drawback of this method is the use of highly toxic solvents.
The drawback of this method is that it cannot handle phrase reordering within the transcripts. .
The main drawback of this method is the chattering phenomenon in the sliding surface.
However, seed dependency is the major drawback of this method (Razvi et al. 2011).
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