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However, some important drawbacks exist.
However, many drawbacks exist in this method, with the most important one being the introduction of a considerable delay in the network.
However, the following drawbacks exist in this approach: (1) This approach is a pure parallel algorithm in view of the computation itself and ignores the physical reality of the underlying problem.
Unfortunately, serious drawbacks exist in these nanomaterials, such as their instability under high temperature treatment [18], degradation during the operation and dispersal into vacuum, which will contaminate the field emitter and thus hinder the electron emission [19], and high surface-to-volume ratio because of small particle size, which will result in low luminescence efficiency.
Presently, drawbacks exist with various extended methods employed in agarose gels to resolve better the DNA bands.
Various possible drawbacks exist to the interpretation of our findings.
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Thus, two major drawback exist in Ulysses: node congestion and load balancing.
Despite many displacement-type EA sensors, a common drawback exists that sensor response rate is relatively slow (typically with target binding equilibrium time ranging from 0.5 to 3 h), which is mainly caused by a suboptimal conformation of the aptamer sequence in the conventional aptamer-cDNA duplex probe containing a relatively large number of aptamer-involved base pairs.
Despite the efficiency and low dissipation of the stream-collide scheme of the discrete-velocity Boltzmann equation, which is nowadays implemented in many lattice Boltzmann solvers, a major drawback exists over alternative discretization schemes, i.e. finite-volume or finite-difference, that is the limitation to Cartesian uniform grids.
Although the approach with firefly luciferases seems to be straightforward, a drawback exists: A spectrum of firefly luciferase is known to change in a pH-dependent manner, which may hamper spectral deconvolution or precise photon counts with specific filters.
However, some drawbacks still exist.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com