It is important to note there are drawbacks to over emphasizing a purely MDA method.
Despite those drawbacks, over the past five years the Morgan Stanley Capital International South Africa Stock Index has delivered a 13%annualized total return in dollar terms versus a 6% rise for the MSCIEmerging Markets Index and a 2% dip for the S&P 500.
Such an analysis has several drawbacks over more quantitative measures (e.g., transcript sequencing, protein detection), but nevertheless provides a preliminary candidate list for identifying mediators of the Gi sensitivity of hES and hiPS cells.
SMOTE encounters some drawbacks including over-generalization and lack of systematizing disjuncts.
Katrina soon made extra clear the many drawbacks of over-enthusiastically caging so many people at once.
-- a drawback that carries over to the sweet, sanitized new musical based on it.
Despite the efficiency and low dissipation of the stream-collide scheme of the discrete-velocity Boltzmann equation, which is nowadays implemented in many lattice Boltzmann solvers, a major drawback exists over alternative discretization schemes, i.e. finite-volume or finite-difference, that is the limitation to Cartesian uniform grids.
In addition, with this framework, we deal with another drawback of gamification: over-competitiveness.
One major drawback associated with over-sampling is that learning on duplicated samples can lead to overfitting [ 14].
A drawback of mTERT over-expression in transgenic mouse studies has been an increased cancer incidence, except for cancer-resistant backgrounds (Artandi et al, 2002; Gonzalez-Suarez et al, 2001; Tomas-Loba et al, 2008).
