The application of biologic agents emerges to compensate for such drawbacks by mimicking, inducing, and regulating the activity of the natural events that happen in the healing area with the purpose of promoting the regeneration of the tissue.
Such agents could have major drawbacks, such as promoting the accumulation of misfolded or aggregate-prone proteins (Grumati et al., 2010; Masiero et al., 2009).
Decreased Treg yields were not observed when human Tregs were expanded in the presence of ATRA, supporting the notion that ATRA could overcome the major drawback of using rapamycin to promote ex vivo Treg expansion.
The widely used rapid detection tests (RDTs) for malaria succumb to many drawbacks which promotes exploration of more efficient economical detection techniques.
Despite their drawbacks, Haüy promoted their use with zeal.
No, the main drawback of corn mazes is that they promote a dangerous amount of introspection and contemplation.
A drawback of selective digestive decontamination is that it may promote overgrowth of MDR gram-positive bacteria, such as MRSA.
In a detailed new report, public health advocate Michele Simon examines the distinct drawbacks of government programs to promote dairy consumption.
It also had inadequate space for showing her creations, a major drawback considering that she was promoting the unusual look of her pieces; many of them combine peacock, duck or other feathers with semiprecious stones.
Though athero-protective, the major drawback of LXR agonists as potential drugs to treat cardiovascular diseases is their stimulating effect on hepatic lipogenesis and increase of plasma triglyceride levels thereby promoting hepato-steatosis [8].
