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By contrast, inhibition of RA signaling during gastrulation and early somitogenesis drastically prevents Pdx1 expression (Fig. 4C; Table 2).
P63 loss of function drastically prevents ectodermal cells to commit to the K5/K14-positive stratified epithelial pathway while gain of function experiments show that ΔNp63 allows this commitment.
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In contrast, calorie restriction and weight reduction can drastically prevent type 2 diabetes, indicating a central role of nutrient excess in the development of diabetes.
Incubation of HOB cells at 4 °C neither altered WST-1 reduction capacity nor led to higher LDH leakage compared to controls (data not shown) but drastically prevented the cellular accumulation of FFSNPs.
Charge injection from the pulled-in electrode into the insulator increases the pull-in voltage drastically, and prevents pulling-in more cantilevers.
Recently, Intel has cut prices drastically, to prevent its onetime rival Advanced Micro Devices from gaining market share.
This means that denting can drastically be prevented by cladding the secondary tubesheet surface with corrosion resistant materials.
These filters limited the number of ESTs for each UTR drastically and prevented us from assigning reliable tissue information to different isoforms.
Then suppose the company quickly adopts a poison pill with a low threshold that prevents or drastically limits further accumulation of stock by the buyer.
The fact that the newly jobless don't have to drastically cut back spending prevents pro-cyclical amplification of the downturn, and human suffering is alleviated, given that falling labour demand is driving rising unemployment.
Met is the amino acid most sensitive to reactive oxygen species, and the oxidation of the Met residue in a protein alters the protein structure (or prevents translation), drastically affecting the function [ 24].
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