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Doubts about his playing system weren't nearly as pronounced inside the club as the media reaction - and Franz Beckenbauer's comments - suggested at the time, but that game proved football pope Pep's fallibility in rather drastic terms: he had bowed to the demands of some of his key players and played a more direct, attacking system despite his better instincts.
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The increase, while drastic in terms of percentage, is not very surprising, said the report's lead author, Gladys Martinez, because awareness of and access to emergency contraceptives have increased in recent years.
Although humans may be inadvertently responsible for some of the Danube region's current biodiversity, Dr. Giosan emphasizes that the human impact on the area over the last century has been drastic in terms of changes in land use, positive and negative.
The results of these minor sequence changes were drastic in terms of scFv solubility, cell compartmentalization and extracellular release.
For example, it has been demonstrated that mutation in many duplicated genes of rice is much slower than in 'singletons' and less drastic in terms of amino acid change [ 26].
But frequent sleep deprivation over four years can have drastic long-term consequences, unleashing a neurological cycle of degeneration.
Given the long time it takes for climate changes to occur, drastic short-term actions don't seem necessary.
Drastic short-term change could be hugely expensive and therefore politically unsustainable in the absence of a strong scientific consensus about its urgency.
His concentration is in positive psychology, and he is particularly fascinated by how optimism and affirmative-oriented mindfulness and mindful practices can lead to drastic long-term effects on people's behavior and cognitive broadening.
They say that in a country like ours where there are strongly established democratic institutions, hate speech (short of incitement to violence) can be pretty much tolerated in the confidence that no drastic, long-term consequences will ensue.
Solving São Paulo's water crisis will require drastic short-term actions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com