Sentence examples for drastic structural change from inspiring English sources

As a result a drastic structural change occurs during thermal annealing, making the buffer layer unstable.

The mutation of the terminal arginine with lysine, another hydrophilic and positively charged amino acid, resulted in a drastic structural change, thus suggesting a major role of the terminal arginine residue in the overall oligopeptide's conformation and, hence, its bioactivity.

BNAS retained about 97% of the specific activity of BCNIT (Fig. 2b), indicating that the protein fused with AsLOV2-SsrA did not suffer any drastic structural change in vitro.

The Ae. longissima mitochondrial genome has undergone a drastic structural change possibly as a result of introducing a new nuclear genome and production of a live alloplasmic line [ 39].

Therefore, a drastic structural change occurs in the miR-206/miR-133b locus; in growth conditions, only the proximal promoter is active and no long-distance interactions occur, while upon differentiation, a DNA loop is observed between distantly located regions, and this correlates with activation of the distal promoter and consolidation of the overall transcription of the locus.

This fact would also explain why the |Δ δ p| values, calculated for 5a1e [Na3(HL)]6– → 1a5e [NareH2L)]6–, are much higher than those for |Δ δ c|, determined for 1a5e H2L8– → 1a5e [Nas(H2L)]6–, as the former process implies a much more drastic structural change.

Cartilage undergoes drastic structural changes during the development of osteoarthritis and cannot heal itself due to a defective chondrocyte response.

However if MPs want to see this aspect of the profession changed then drastic structural changes in the way that research is funded by major charities and the Research Councils alike will be required.

Mrs. Merkel and other German officials fear that giving in to the calls for collective bonds or using the European Central Bank as a lender of last resort will ease pressure on the debtor nations, allowing them to avert the drastic structural changes that Berlin says that they need to make to become competitive, while making Germany and other creditors liable for their debts.

However, such drastic structural changes appear to be unnecessary for the three d-LDHs, which exhibit apparently much smaller changes in catalytic activity due to the allosteric transition than the l-LDHs.

Since D-form peptides are resistant to natural enzyme degradation, such drastic structural changes may be exploited for fabricating molecular sensors to detect minute environmental changes.