In contrast, expression of activated MEK1 or MEK2 led to drastic morphological changes accompanied by loss of cell-cell contacts; the cells adopted a spindle-like fibroblast morphology, were more refractile and formed multilayers.
We found that the levels of AQP1 protein expression on cultured human astrocytes were not affected by exposure to Aβ1-42 peptide at least within a 48 h-observation period, although we observed a drastic change in morphology of astrocytes, exhibiting the morphology with ruffled cell-surface membranes (Supplementary Fig. 4).
We have recently demonstrated that through a sol gel route, superconductor crystallization in the presence of simple biopolymers results in a drastic alteration of morphology, producing technologically useful nanowires and porous architectures.
A process of developmental change whereby a larva reaches adulthood only after a drastic change in morphology; occurs in most amphibians and insects, for some insects, this change may include another stage (pupa) before the adult stage; metamorphose- v. motile -- Able to move oneself about, capable of self-locomotion.
Such drastic changes in morphology were accompanied by the largest number (about 13,000) of genes with different expression levels.
The data show that the TYP and LON forms are very similar genetically in spite of drastic differences in morphology, life history traits, and ecological preferences.
By contrast, recombination between lineages is often accompanied by drastic changes in morphology, performance and fitness [ 79, 82- 84], even involving diversification into new habitats [ 85].
Less expected is the nearly complete genetic identity of the TYP and LON forms, because these forms have drastic differences in morphology, life history traits, and ecology.
- Moreover, mitochondria and peroxisomes are highly dynamic organelles that can undergo drastic changes in morphology and number to accomplish cellular needs (Fig. 1).
The long branches from their common node are consistent with drastic differences in morphology, life cycle (Oborník et al., 2012), plastid (Janouškovec et al., 2010) and mitochondrial genomes (Flegontov et al., 2015) between the two chromerids.
