Sentence examples for drastic loss of function from inspiring English sources

Frameshift mutations can lead to drastic loss of function and occur through the addition or deletion of one or more DNA bases.

Another type of point mutation that can lead to drastic loss of function is a frameshift mutation, the addition or deletion of one or more DNA bases.

Instead, we show that LRPPRC deficiency is associated with an ATP synthase assembly defect leading to a drastic loss of function of this enzyme.

Snf7 mutants of A51E, L55E, L67E, V126E, M130E and I133E led to drastic loss-of-function, with sorting efficiencies from 9%to55%5% in vivo, and were unable to assemble into protofilaments in vitro.

For these cancers, radiation therapy is a common treatment modality, but irradiation of this region often results in secondary side-effects in non-diseased tissues, including drastic loss of salivary gland function.

Nef alleles lacking the CD3 downmodulation function emerged only after the drastic loss of CD4+ T cells and only in the context of X4-tropic SIVsmm variants.

In strong loss-of-function armO43A01 maternal and zygotic (M/Z) mutants (hereafter referred to as armO43A01 (M/Z)) no intact cuticle is made because loss of Arm leads to a drastic loss of cell-cell adhesion in the epidermis.

He felt a tingling in his arm and a drastic loss of arm strength.

Low-diversity libraries can interfere in correct cluster identification, resulting in drastic loss of data output.

A drastic loss of the usual personal, emotional and intellectual coordinates.

The stem cells involved in bone marrow transplants "can regenerate drastic loss of tissue," he said.