Such drastic invasions of new sequence elements in flanking regions result in the de novo creation of regulatory elements involved in the transcriptional and post-transcriptional regulation of gene expression that differentiate gene copies in their function.
These factors were very highly expressed in the aggressive, human mesenchymal breast cancer cells, and depletion of three of these factors (PRKRIR, PCBP4 and TSC22D1) in these cells led to a drastic loss in their wound healing and invasion capacity.
The National Trust has warned the Government that drastic action must be taken to curb the invasion of two deadly fungal diseases which could affect all public gardens in the UK within 20 years.
Obama won't try more stringent steps against actual sectors of the Russian economy unless something truly drastic and new, such as an actual Russian invasion of Ukraine proper.
The small archipelago of Tl'chés, in coastal British Columbia, has gone through drastic social-ecological change culminating in the decline of traditional management practices, invasion of exotic plant species and, in the early 1960s, land abandonment.
The invasion of non-native signal crayfish into European ecosystems has resulted in a drastic reduction of native European crayfish, with adverse effects on ecosystems and fisheries.
