"We saw a very drastic impact," said Dr. Arata Kochi, chief of malaria for the W.H.O.
The restructuring and consequent job insecurity are having a drastic impact on staff morale.
The method you choose can have a pretty drastic impact on your tax bill, at least in some cases.
"He's aware of all those little details that at first may seem insignificant but have drastic impact on customers' perceptions".
While the price war has affected the gross margins at both companies, the moves have had a more drastic impact on A.M.D. this last year.
The outage will take several days to fix, and could have a drastic impact around the region and across the globe.
Because of its residual nature, even relatively small movements in spending or receipts can have a drastic impact on the deficit.
Pete Carroll, the U.S.C. coach and former N.F.L. head coach, said he did not think relaxed draft rules would have a drastic impact on college football.
Bank of America, the nation's biggest credit card lender and retail bank, said the new rules could have a drastic impact.
Although financial damages, if any, would be determined later, the decision could have a drastic impact on the three-year-old company, best known for operating a Web site where unsigned artists distribute their music free.
But they acknowledge that a circumcision drive in the United States would be unlikely to have a drastic impact: the procedure does not seem to protect those at greatest risk here, men who have sex with men.
