Although Miramar et al. described that some variants such as K3083E or 9475A>G introduce a drastic amino acid exchange (lysine to glutamine) and represent functional disturbance in BRCA2 protein [ 40], they are still known as a nonpathogenic polymorphism.
This year, in exchange for drastic austerity measures, Greece's government agreed to an aid package (its second) with the European Union and the International Monetary Fund, totalling $174 billion.
In exchange a drastic reduction in the biofilm development was observed in the case of textile fibers coated with nanoparticles; these results confirm the quantitative, culture-based assay.
Inhibition of this enzyme during simulations showed a drastic change in 54 exchange reaction fluxes pertaining to carbohydrate, cofactor (thiamine, pyridoxine, bilirubin), lipid, and nucleotide metabolism.
There is, therefore, no sign from the annual National People's Congress that China will make drastic changes on its exchange-rate policy, reflecting in part its confidence that the burden of the proof lies more with the Trump administration.
That should prove crucial as the exchange copes with drastic technological change and competition from Nasdaq and other rivals.
The troika stepped in during the spring of 2010, and again in 2012, to orchestrate bailouts of the Greek government, offering two hundred and forty billion euros in loans in exchange for a drastic reduction in government spending and other measures to make the Greek economy more competitive.
The renewed push toward final passage of a bankruptcy overhaul has alarmed consumer advocates, who say that the bill is a reward to banks and credit card companies in exchange for a drastic increase in their campaign contributions to both parties.
That promise had been made in exchange for a drastic reduction in employee rights and liberties that was accepted by the unions, starting in Pomigliano, Mirafiori, Bertone and finally throughout the entire Fiat group.
Detailed phylogenetic analysis allows formulation of a hypothesis for the evolution of the TAM: Although TamB was already present from the earliest-branching Phyla, TamA is the result of a gene duplication of BamA followed by drastic adaptation or partial sequence exchange of two POTRA domains, resulting in the TAM complex exemplified today in E. coli.
