Sentence examples for drastic cell from inspiring English sources

Prolonged insulin resistance leads to an overload of the pancreatic cells which produce insulin, resulting in drastic cell death and diabetes.

A central process in cancer metastasis is cell motility, which involves drastic cell shape changes driven by cytoskeletal remodeling (Waterman-Storer and Salmon, 1999; Olson and Sahai, 2009; Wells et al., 2013).

Flow cytometry analysis revealed that compound 4i showed drastic cell cycle perturbations due to concentration dependant increase in the sub-G0 region which comprises of both the apoptotic and debris fraction, thus implying the extent of cell death.

Remarkably, it was reported that upon pharmacological inhibition of matrix metalloproteinases, cells, instead of proteolytically degrading their local environment, were forced to "squeeze" through a collagen fiber network accompanied by drastic cell and nuclear deformation upon migration [7].

Drastic cell elongation and migration are hallmarks of H. pylori-infected epithelial cells in vitro.

Early fruit growth in tomato, usually referring to the growth within 2 3 weeks after anthesis, is characterized by rapid cell division and drastic cell expansion.

The analysis of individual cells carried out using fluorescent in situ hybridization paradoxically suggest a drastic cell-cell variability in genome content, leading to the interpretation that the production of a cell with an advantageous genome change may be an extremely rare event in breast tumourigenesis.

Nevertheless, the very same treatment resulted in drastic Akata cell death, suggesting that the latter could not be prevented by the induction of hIL-10 expression.

This identifies a critical role for actin bundles in promoting the cortical inhomogeneity and cellular pressure that have been postulated to mediate symmetry breaking to drive this drastic polarized cell shape change (Ruprecht et al., 2015).

Furthermore, we demonstrated that ablation of this protein by antisense technology causes devastating effects on tumor cells through a drastic reduction of cell proliferation and massive induction of apoptosis, while non-transformed cells remain unaffected.

Preliminary data obtained in breast tumor cells showed a drastic impairment of cell motility in response to PtAcD occurring through a novel mechanism mediated by ERK1/2 activation.